BDBM35088 biarylether alcohol quinoline, 5a

SMILES: OCc1cccc(Oc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(cccc23)C(F)(F)F)c1

InChI Key: InChIKey=JZHGBILVGRSOHN-UHFFFAOYSA-N

Data: 2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35088   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Liver X Receptor beta (LXR-beta) (Homo sapiens (Human))	BDBM35088 (biarylether alcohol quinoline, 5a) Show SMILES OCc1cccc(Oc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(cccc23)C(F)(F)F)c1 Show InChI InChI=1S/C30H22F3NO2/c31-30(32,33)27-14-6-13-26-28(23(18-34-29(26)27)15-20-7-2-1-3-8-20)22-10-5-12-25(17-22)36-24-11-4-9-21(16-24)19-35/h1-14,16-18,35H,15,19H2	PDB MMDB KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11.7	n/a	1.03E+3	n/a	n/a	7.4	4
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXRbeta coated flash plates. Each concentration of ...				Bioorg Med Chem 17: 8086-92 (2009) Article DOI: 10.1016/j.bmc.2009.10.001 BindingDB Entry DOI: 10.7270/Q2VH5M54
					More data for this Ligand-Target Pair
Liver X Receptor alpha (LXR-alpha) (Homo sapiens (Human))	BDBM35088 (biarylether alcohol quinoline, 5a) Show SMILES OCc1cccc(Oc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(cccc23)C(F)(F)F)c1 Show InChI InChI=1S/C30H22F3NO2/c31-30(32,33)27-14-6-13-26-28(23(18-34-29(26)27)15-20-7-2-1-3-8-20)22-10-5-12-25(17-22)36-24-11-4-9-21(16-24)19-35/h1-14,16-18,35H,15,19H2	PDB MMDB Reactome pathway B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXRalpha coated flash plates. Each concentration of...				Bioorg Med Chem 17: 8086-92 (2009) Article DOI: 10.1016/j.bmc.2009.10.001 BindingDB Entry DOI: 10.7270/Q2VH5M54
					More data for this Ligand-Target Pair