BDBM350884 US9795608, Compound 14

SMILES: Cc1ccc(COc2cc(F)cc(Oc3ccc(cc3)-n3nc(C4CCOCC4)c4ncnc(N)c34)c2)cn1

InChI Key: InChIKey=UQXXQRNFBDATRL-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 350884   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM350884 (US9795608, Compound 14) Show SMILES Cc1ccc(COc2cc(F)cc(Oc3ccc(cc3)-n3nc(C4CCOCC4)c4ncnc(N)c34)c2)cn1 Show InChI InChI=1S/C29H27FN6O3/c1-18-2-3-19(15-32-18)16-38-24-12-21(30)13-25(14-24)39-23-6-4-22(5-7-23)36-28-27(33-17-34-29(28)31)26(35-36)20-8-10-37-11-9-20/h2-7,12-15,17,20H,8-11,16H2,1H3,(H2,31,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
PHARMASCIENCE, INC. US Patent					Assay Description Fluorescence polarization-based kinase assays were performed in 384 well-plate format using histidine tagged recombinant human full-length Bruton Aga...				US Patent US9795608 (2017) BindingDB Entry DOI: 10.7270/Q29K4DCP
					More data for this Ligand-Target Pair