BDBM350886 2-Cyclohexylmethylthio-3-phenyl-4-oxo-3,4-dihydroquinazoline::US9796687, Compound 1

SMILES: O=c1n(c(SCC2CCCCC2)nc2ccccc12)-c1ccccc1

InChI Key: InChIKey=FPNFDIFIGCSJIO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 350886   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 7 (Homo sapiens (Human))	BDBM350886 (2-Cyclohexylmethylthio-3-phenyl-4-oxo-3,4-dihydroq...) Show SMILES O=c1n(c(SCC2CCCCC2)nc2ccccc12)-c1ccccc1 Show InChI InChI=1S/C21H22N2OS/c24-20-18-13-7-8-14-19(18)22-21(23(20)17-11-5-2-6-12-17)25-15-16-9-3-1-4-10-16/h2,5-8,11-14,16H,1,3-4,9-10,15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS US Patent					Assay Description Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...				US Patent US9796687 (2017) BindingDB Entry DOI: 10.7270/Q2NV9MDC
					More data for this Ligand-Target Pair