BDBM350894 2-Ethylthio-3-phenyl-4-oxo-3,4-dihydroquinazoline ::US9796687, Compound 16

SMILES: CCSc1nc2ccccc2c(=O)n1-c1ccccc1

InChI Key: InChIKey=CFELAOYYJGZQMD-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 350894   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM350894 (2-Ethylthio-3-phenyl-4-oxo-3,4-dihydroquinazoline ...) Show SMILES CCSc1nc2ccccc2c(=O)n1-c1ccccc1 Show InChI InChI=1S/C16H14N2OS/c1-2-20-16-17-14-11-7-6-10-13(14)15(19)18(16)12-8-4-3-5-9-12/h3-11H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE7A1 using [3H]AMP after 20 mins by scintillation proximity assay				Eur J Med Chem 70: 781-8 (2013) Article DOI: 10.1016/j.ejmech.2013.10.035 BindingDB Entry DOI: 10.7270/Q2CR5X88
					More data for this Ligand-Target Pair
Phosphodiesterase 7 (Homo sapiens (Human))	BDBM350894 (2-Ethylthio-3-phenyl-4-oxo-3,4-dihydroquinazoline ...) Show SMILES CCSc1nc2ccccc2c(=O)n1-c1ccccc1 Show InChI InChI=1S/C16H14N2OS/c1-2-20-16-17-14-11-7-6-10-13(14)15(19)18(16)12-8-4-3-5-9-12/h3-11H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS US Patent					Assay Description Measurement of PDE7 inhibition was carried out using a commercial phosphodiesterase activity measurement kit.Some of the compounds of the present inv...				US Patent US9796687 (2017) BindingDB Entry DOI: 10.7270/Q2NV9MDC
					More data for this Ligand-Target Pair