BDBM35114 biarylether amide quinoline, 4o

SMILES: Cc1cnc2c(Cl)cccc2c1-c1cccc(Oc2cccc(c2)C(=O)N2CCCCC2)c1

InChI Key: InChIKey=PWFODDIPAXPLMJ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35114   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Liver X Receptor alpha (LXR-alpha) (Homo sapiens (Human))	BDBM35114 (biarylether amide quinoline, 4o) Show SMILES Cc1cnc2c(Cl)cccc2c1-c1cccc(Oc2cccc(c2)C(=O)N2CCCCC2)c1 Show InChI InChI=1S/C28H25ClN2O2/c1-19-18-30-27-24(12-7-13-25(27)29)26(19)20-8-5-10-22(16-20)33-23-11-6-9-21(17-23)28(32)31-14-3-2-4-15-31/h5-13,16-18H,2-4,14-15H2,1H3	PDB MMDB Reactome pathway B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 17: 1663-70 (2009) Article DOI: 10.1016/j.bmc.2008.12.048 BindingDB Entry DOI: 10.7270/Q2QR4VGV
					More data for this Ligand-Target Pair
Liver X Receptor beta (LXR-beta) (Homo sapiens (Human))	BDBM35114 (biarylether amide quinoline, 4o) Show SMILES Cc1cnc2c(Cl)cccc2c1-c1cccc(Oc2cccc(c2)C(=O)N2CCCCC2)c1 Show InChI InChI=1S/C28H25ClN2O2/c1-19-18-30-27-24(12-7-13-25(27)29)26(19)20-8-5-10-22(16-20)33-23-11-6-9-21(17-23)28(32)31-14-3-2-4-15-31/h5-13,16-18H,2-4,14-15H2,1H3	PDB MMDB KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	7.4	4
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 17: 1663-70 (2009) Article DOI: 10.1016/j.bmc.2008.12.048 BindingDB Entry DOI: 10.7270/Q2QR4VGV
					More data for this Ligand-Target Pair