BDBM351399 1,4:3,6-dianhydro-2-deoxy-5-O-[4-[(3,4- dichlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-2-fluoro-D-iditol::US9796704, Entry 119

SMILES: COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12

InChI Key: InChIKey=ZDHUWTTUQHECMO-FCDRMGDPSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 351399   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM351399 (1,4:3,6-dianhydro-2-deoxy-5-O-[4-[(3,4- dichloroph...) Show SMILES COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12 |r| Show InChI InChI=1S/C21H18Cl2FN3O4/c1-28-16-5-11-15(6-17(16)31-18-8-30-19-14(24)7-29-20(18)19)25-9-26-21(11)27-10-2-3-12(22)13(23)4-10/h2-6,9,14,18-20H,7-8H2,1H3,(H,25,26,27)/t14-,18-,19+,20+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
SYMPHONY EVOLUTION, INC. US Patent					Assay Description In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...				US Patent US9796704 (2017) BindingDB Entry DOI: 10.7270/Q28K7C6V
					More data for this Ligand-Target Pair
Ephrin type-A receptor 2 (Homo sapiens (Human))	BDBM351399 (1,4:3,6-dianhydro-2-deoxy-5-O-[4-[(3,4- dichloroph...) Show SMILES COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12 |r| Show InChI InChI=1S/C21H18Cl2FN3O4/c1-28-16-5-11-15(6-17(16)31-18-8-30-19-14(24)7-29-20(18)19)25-9-26-21(11)27-10-2-3-12(22)13(23)4-10/h2-6,9,14,18-20H,7-8H2,1H3,(H,25,26,27)/t14-,18-,19+,20+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
SYMPHONY EVOLUTION, INC. US Patent					Assay Description In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...				US Patent US9796704 (2017) BindingDB Entry DOI: 10.7270/Q28K7C6V
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM351399 (1,4:3,6-dianhydro-2-deoxy-5-O-[4-[(3,4- dichloroph...) Show SMILES COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12 |r| Show InChI InChI=1S/C21H18Cl2FN3O4/c1-28-16-5-11-15(6-17(16)31-18-8-30-19-14(24)7-29-20(18)19)25-9-26-21(11)27-10-2-3-12(22)13(23)4-10/h2-6,9,14,18-20H,7-8H2,1H3,(H,25,26,27)/t14-,18-,19+,20+/m1/s1	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
SYMPHONY EVOLUTION, INC. US Patent					Assay Description In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...				US Patent US9796704 (2017) BindingDB Entry DOI: 10.7270/Q28K7C6V
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM351399 (1,4:3,6-dianhydro-2-deoxy-5-O-[4-[(3,4- dichloroph...) Show SMILES COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12 |r| Show InChI InChI=1S/C21H18Cl2FN3O4/c1-28-16-5-11-15(6-17(16)31-18-8-30-19-14(24)7-29-20(18)19)25-9-26-21(11)27-10-2-3-12(22)13(23)4-10/h2-6,9,14,18-20H,7-8H2,1H3,(H,25,26,27)/t14-,18-,19+,20+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
SYMPHONY EVOLUTION, INC. US Patent					Assay Description In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...				US Patent US9796704 (2017) BindingDB Entry DOI: 10.7270/Q28K7C6V
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM351399 (1,4:3,6-dianhydro-2-deoxy-5-O-[4-[(3,4- dichloroph...) Show SMILES COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12 |r| Show InChI InChI=1S/C21H18Cl2FN3O4/c1-28-16-5-11-15(6-17(16)31-18-8-30-19-14(24)7-29-20(18)19)25-9-26-21(11)27-10-2-3-12(22)13(23)4-10/h2-6,9,14,18-20H,7-8H2,1H3,(H,25,26,27)/t14-,18-,19+,20+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
SYMPHONY EVOLUTION, INC. US Patent					Assay Description In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...				US Patent US9796704 (2017) BindingDB Entry DOI: 10.7270/Q28K7C6V
					More data for this Ligand-Target Pair