null

SMILES: COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1ccc2nc(cc(Cl)c2c1)C(F)(F)F

InChI Key: InChIKey=QEIAACVSNFOMGZ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 351516   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM351516 (7-({[4-chloro-2-(trifluoromethyl)quinolin-6- yl]me...) Show SMILES COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1ccc2nc(cc(Cl)c2c1)C(F)(F)F Show InChI InChI=1S/C26H16Cl3F3N4O2/c1-37-22-8-16-21(33-12-34-25(16)35-14-3-4-17(27)19(29)7-14)10-23(22)38-11-13-2-5-20-15(6-13)18(28)9-24(36-20)26(30,31)32/h2-10,12H,11H2,1H3,(H,33,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
SYMPHONY EVOLUTION, INC. US Patent					Assay Description In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...				US Patent US9796704 (2017) BindingDB Entry DOI: 10.7270/Q28K7C6V
					More data for this Ligand-Target Pair
Ephrin type-A receptor 2 (Homo sapiens (Human))	BDBM351516 (7-({[4-chloro-2-(trifluoromethyl)quinolin-6- yl]me...) Show SMILES COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1ccc2nc(cc(Cl)c2c1)C(F)(F)F Show InChI InChI=1S/C26H16Cl3F3N4O2/c1-37-22-8-16-21(33-12-34-25(16)35-14-3-4-17(27)19(29)7-14)10-23(22)38-11-13-2-5-20-15(6-13)18(28)9-24(36-20)26(30,31)32/h2-10,12H,11H2,1H3,(H,33,34,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
SYMPHONY EVOLUTION, INC. US Patent					Assay Description In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...				US Patent US9796704 (2017) BindingDB Entry DOI: 10.7270/Q28K7C6V
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM351516 (7-({[4-chloro-2-(trifluoromethyl)quinolin-6- yl]me...) Show SMILES COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1ccc2nc(cc(Cl)c2c1)C(F)(F)F Show InChI InChI=1S/C26H16Cl3F3N4O2/c1-37-22-8-16-21(33-12-34-25(16)35-14-3-4-17(27)19(29)7-14)10-23(22)38-11-13-2-5-20-15(6-13)18(28)9-24(36-20)26(30,31)32/h2-10,12H,11H2,1H3,(H,33,34,35)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
SYMPHONY EVOLUTION, INC. US Patent					Assay Description In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...				US Patent US9796704 (2017) BindingDB Entry DOI: 10.7270/Q28K7C6V
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM351516 (7-({[4-chloro-2-(trifluoromethyl)quinolin-6- yl]me...) Show SMILES COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1ccc2nc(cc(Cl)c2c1)C(F)(F)F Show InChI InChI=1S/C26H16Cl3F3N4O2/c1-37-22-8-16-21(33-12-34-25(16)35-14-3-4-17(27)19(29)7-14)10-23(22)38-11-13-2-5-20-15(6-13)18(28)9-24(36-20)26(30,31)32/h2-10,12H,11H2,1H3,(H,33,34,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
SYMPHONY EVOLUTION, INC. US Patent					Assay Description In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...				US Patent US9796704 (2017) BindingDB Entry DOI: 10.7270/Q28K7C6V
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM351516 (7-({[4-chloro-2-(trifluoromethyl)quinolin-6- yl]me...) Show SMILES COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1ccc2nc(cc(Cl)c2c1)C(F)(F)F Show InChI InChI=1S/C26H16Cl3F3N4O2/c1-37-22-8-16-21(33-12-34-25(16)35-14-3-4-17(27)19(29)7-14)10-23(22)38-11-13-2-5-20-15(6-13)18(28)9-24(36-20)26(30,31)32/h2-10,12H,11H2,1H3,(H,33,34,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
SYMPHONY EVOLUTION, INC. US Patent					Assay Description In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...				US Patent US9796704 (2017) BindingDB Entry DOI: 10.7270/Q28K7C6V
					More data for this Ligand-Target Pair