null

SMILES: CCN1CCC(CC1)c1nc(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)no1

InChI Key: InChIKey=QWTRRGLWVSSIML-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 351518   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM351518 (N-(3,4-dichlorophenyl)-7-({[5-(1- ethylpiperidin-4...) Show SMILES CCN1CCC(CC1)c1nc(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)no1 Show InChI InChI=1S/C25H26Cl2N6O3/c1-3-33-8-6-15(7-9-33)25-31-23(32-36-25)13-35-22-12-20-17(11-21(22)34-2)24(29-14-28-20)30-16-4-5-18(26)19(27)10-16/h4-5,10-12,14-15H,3,6-9,13H2,1-2H3,(H,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
SYMPHONY EVOLUTION, INC. US Patent					Assay Description In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...				US Patent US9796704 (2017) BindingDB Entry DOI: 10.7270/Q28K7C6V
					More data for this Ligand-Target Pair
Ephrin type-A receptor 2 (Homo sapiens (Human))	BDBM351518 (N-(3,4-dichlorophenyl)-7-({[5-(1- ethylpiperidin-4...) Show SMILES CCN1CCC(CC1)c1nc(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)no1 Show InChI InChI=1S/C25H26Cl2N6O3/c1-3-33-8-6-15(7-9-33)25-31-23(32-36-25)13-35-22-12-20-17(11-21(22)34-2)24(29-14-28-20)30-16-4-5-18(26)19(27)10-16/h4-5,10-12,14-15H,3,6-9,13H2,1-2H3,(H,28,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
SYMPHONY EVOLUTION, INC. US Patent					Assay Description In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...				US Patent US9796704 (2017) BindingDB Entry DOI: 10.7270/Q28K7C6V
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM351518 (N-(3,4-dichlorophenyl)-7-({[5-(1- ethylpiperidin-4...) Show SMILES CCN1CCC(CC1)c1nc(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)no1 Show InChI InChI=1S/C25H26Cl2N6O3/c1-3-33-8-6-15(7-9-33)25-31-23(32-36-25)13-35-22-12-20-17(11-21(22)34-2)24(29-14-28-20)30-16-4-5-18(26)19(27)10-16/h4-5,10-12,14-15H,3,6-9,13H2,1-2H3,(H,28,29,30)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
SYMPHONY EVOLUTION, INC. US Patent					Assay Description In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...				US Patent US9796704 (2017) BindingDB Entry DOI: 10.7270/Q28K7C6V
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM351518 (N-(3,4-dichlorophenyl)-7-({[5-(1- ethylpiperidin-4...) Show SMILES CCN1CCC(CC1)c1nc(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)no1 Show InChI InChI=1S/C25H26Cl2N6O3/c1-3-33-8-6-15(7-9-33)25-31-23(32-36-25)13-35-22-12-20-17(11-21(22)34-2)24(29-14-28-20)30-16-4-5-18(26)19(27)10-16/h4-5,10-12,14-15H,3,6-9,13H2,1-2H3,(H,28,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
SYMPHONY EVOLUTION, INC. US Patent					Assay Description In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...				US Patent US9796704 (2017) BindingDB Entry DOI: 10.7270/Q28K7C6V
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM351518 (N-(3,4-dichlorophenyl)-7-({[5-(1- ethylpiperidin-4...) Show SMILES CCN1CCC(CC1)c1nc(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)no1 Show InChI InChI=1S/C25H26Cl2N6O3/c1-3-33-8-6-15(7-9-33)25-31-23(32-36-25)13-35-22-12-20-17(11-21(22)34-2)24(29-14-28-20)30-16-4-5-18(26)19(27)10-16/h4-5,10-12,14-15H,3,6-9,13H2,1-2H3,(H,28,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
SYMPHONY EVOLUTION, INC. US Patent					Assay Description In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...				US Patent US9796704 (2017) BindingDB Entry DOI: 10.7270/Q28K7C6V
					More data for this Ligand-Target Pair