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SMILES: COc1ccc(COc2cccc(Oc3ccc(cc3)-c3nn(C4CCCC4)c4ncnc(N)c34)c2)cc1

InChI Key: InChIKey=IRDNAQRTGRSOOB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 351765   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM351765
PNG
(US9796716, Compound 11)
Show SMILES COc1ccc(COc2cccc(Oc3ccc(cc3)-c3nn(C4CCCC4)c4ncnc(N)c34)c2)cc1
Show InChI InChI=1S/C30H29N5O3/c1-36-23-13-9-20(10-14-23)18-37-25-7-4-8-26(17-25)38-24-15-11-21(12-16-24)28-27-29(31)32-19-33-30(27)35(34-28)22-5-2-3-6-22/h4,7-17,19,22H,2-3,5-6,18H2,1H3,(H2,31,32,33)
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US Patent
<100n/an/an/an/an/an/an/an/a



PHARMASCIENCE, INC.

US Patent


Assay Description
Fluorescence polarization-based kinase assays were performed in 384 well-plate format using histidine tagged recombinant human full-length Bruton Aga...

US Patent US9796716 (2017)


BindingDB Entry DOI: 10.7270/Q2MW2K8J
More data for this
Ligand-Target Pair