BindingDB PrimarySearch_ki

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BDBM352290 US9802939, I-9

SMILES: COC(=O)Nc1ccc2-c3c[nH]c(n3)C(C\C=C\CC(=O)Nc2c1)NC(=O)c1cc(no1)-c1cccc(Cl)c1

InChI Key:

Data: 1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 352290
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Coagulation factor XI (Homo sapiens (Human))	BDBM352290 (US9802939, I-9) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.87E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...				US Patent US9802939 (2017) BindingDB Entry DOI: 10.7270/Q2X63Q37
Bristol-Myers Squibb Company US Patent					More data for this Ligand-Target Pair