BDBM35233 3-(phenylsulfonyl)-1H-indole, 27a

SMILES: CN(C)CCc1ccc2[nH]cc(c2c1)S(=O)(=O)c1ccccc1

InChI Key: InChIKey=NQKROFWTWKENTC-UHFFFAOYSA-N

Data: 1 Other

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 35233   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM35233 (3-(phenylsulfonyl)-1H-indole, 27a) Show SMILES CN(C)CCc1ccc2[nH]cc(c2c1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C18H20N2O2S/c1-20(2)11-10-14-8-9-17-16(12-14)18(13-19-17)23(21,22)15-6-4-3-5-7-15/h3-9,12-13,19H,10-11H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.4	37
Wyeth Research					Assay Description IC50 Values were obtained from inhibition of norepinephrine uptake in MDCK-Net6 cells, stably transfected with the human NET.				Bioorg Med Chem 17: 7802-15 (2009) Article DOI: 10.1016/j.bmc.2009.09.023 BindingDB Entry DOI: 10.7270/Q26Q1VK2
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