BDBM352390 5-[5-(7-Ethyl-7H-imidazo[4,5-c]pyridazin-4-yl)-2-fluorophenyl]-6-methoxy-2-methyl-2,3-dihydro-1H-isoindol-1-one::US9802945, 1

SMILES: CCn1cnc2c(cnnc12)-c1ccc(F)c(c1)-c1cc2CN(C)C(=O)c2cc1CO

InChI Key: InChIKey=ZXBDRFOZYPKXKS-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 352390   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM352390 (5-[5-(7-Ethyl-7H-imidazo[4,5-c]pyridazin-4-yl)-2-f...) Show SMILES CCn1cnc2c(cnnc12)-c1ccc(F)c(c1)-c1cc2CN(C)C(=O)c2cc1CO Show InChI InChI=1S/C23H20FN5O2/c1-3-29-12-25-21-19(9-26-27-22(21)29)13-4-5-20(24)18(6-13)16-7-14-10-28(2)23(31)17(14)8-15(16)11-30/h4-9,12,30H,3,10-11H2,1-2H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US9802945 (2017) BindingDB Entry DOI: 10.7270/Q2NP26JT
					More data for this Ligand-Target Pair