BDBM352400 5′-(7-Cyclopropyl-7H-imidazo[4,5-c]pyridazin-4-yl)-2′-fluoro-N-methylbiphenyl-4-carboxamide::US9802945, 11

SMILES: CNC(=O)c1ccc(cc1)-c1cc(ccc1F)-c1cnnc2n(cnc12)C1CC1

InChI Key: InChIKey=LBUUNEXUAXYFLF-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 352400   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM352400 (5′-(7-Cyclopropyl-7H-imidazo[4,5-c]pyridazin...) Show SMILES CNC(=O)c1ccc(cc1)-c1cc(ccc1F)-c1cnnc2n(cnc12)C1CC1 Show InChI InChI=1S/C22H18FN5O/c1-24-22(29)14-4-2-13(3-5-14)17-10-15(6-9-19(17)23)18-11-26-27-21-20(18)25-12-28(21)16-7-8-16/h2-6,9-12,16H,7-8H2,1H3,(H,24,29)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	20.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US9802945 (2017) BindingDB Entry DOI: 10.7270/Q2NP26JT
					More data for this Ligand-Target Pair