BDBM352401 2′-Fluoro-5′-[7-(propan-2-yl)-7H-imidazo[4,5-c]pyridazin-4-yl]biphenyl-4-carboxamide::US9802945, 12

SMILES: CC(C)n1cnc2c(cnnc12)-c1ccc(F)c(c1)-c1ccc(cc1)C(N)=O

InChI Key: InChIKey=QVXRSKRJJFTHLM-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 352401   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM352401 (2′-Fluoro-5′-[7-(propan-2-yl)-7H-imida...) Show SMILES CC(C)n1cnc2c(cnnc12)-c1ccc(F)c(c1)-c1ccc(cc1)C(N)=O Show InChI InChI=1S/C21H18FN5O/c1-12(2)27-11-24-19-17(10-25-26-21(19)27)15-7-8-18(22)16(9-15)13-3-5-14(6-4-13)20(23)28/h3-12H,1-2H3,(H2,23,28)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	10.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US9802945 (2017) BindingDB Entry DOI: 10.7270/Q2NP26JT
					More data for this Ligand-Target Pair