BDBM3527 US8524699, 18

SMILES: O=c1c(c[nH]n1-c1cc(ncn1)N1CCOCC1)-c1cccnc1

InChI Key: InChIKey=FYANMSVJCQRSAU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3527   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hypoxia-inducible factor prolyl hydroxylase 4 (HIF) (Homo sapiens (Human))	BDBM3527 (US8524699, 18) Show SMILES O=c1c(c[nH]n1-c1cc(ncn1)N1CCOCC1)-c1cccnc1 Show InChI InChI=1S/C16H16N6O2/c23-16-13(12-2-1-3-17-9-12)10-20-22(16)15-8-14(18-11-19-15)21-4-6-24-7-5-21/h1-3,8-11,20H,4-7H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	180	n/a	n/a	n/a	n/a	7.5	25
Bayer Intellectual Property GmbH US Patent					Assay Description In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.				US Patent US8524699 (2013) BindingDB Entry DOI: 10.7270/Q2TB15J4
					More data for this Ligand-Target Pair