BDBM35390 2-(2-keto-1-methyl-2-piperidino-ethyl)-4-methyl-benzothiopheno[2,3-d]pyridazin-1-one::4-methyl-2-(1-methyl-2-oxo-2-piperidin-1-ylethyl)[1]benzothieno[2,3-d]pyridazin-1(2H)-one::4-methyl-2-(1-oxidanylidene-1-piperidin-1-yl-propan-2-yl)-[1]benzothiolo[2,3-d]pyridazin-1-one::4-methyl-2-(1-oxo-1-piperidin-1-ylpropan-2-yl)-[1]benzothiolo[2,3-d]pyridazin-1-one::4-methyl-2-[1-oxo-1-(1-piperidinyl)propan-2-yl]-[1]benzothiolo[2,3-d]pyridazin-1-one::MLS000093662::SMR000029280::cid_3238280

SMILES: CC(C(=O)N1CCCCC1)n1nc(C)c2sc3ccccc3c2c1=O

InChI Key: InChIKey=DOTOMXRXJJNUOG-UHFFFAOYSA-N

Data: 3 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 35390   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual Specificity Protein Phosphatase 1 (Homo sapiens (Human))	BDBM35390 (2-(2-keto-1-methyl-2-piperidino-ethyl)-4-methyl-be...) Show SMILES CC(C(=O)N1CCCCC1)n1nc(C)c2sc3ccccc3c2c1=O Show InChI InChI=1S/C19H21N3O2S/c1-12-17-16(14-8-4-5-9-15(14)25-17)19(24)22(20-12)13(2)18(23)21-10-6-3-7-11-21/h4-5,8-9,13H,3,6-7,10-11H2,1-2H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	7.0	22
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay					Assay Description The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2F769WQ
					More data for this Ligand-Target Pair
MKP-3 (Rattus norvegicus)	BDBM35390 (2-(2-keto-1-methyl-2-piperidino-ethyl)-4-methyl-be...) Show SMILES CC(C(=O)N1CCCCC1)n1nc(C)c2sc3ccccc3c2c1=O Show InChI InChI=1S/C19H21N3O2S/c1-12-17-16(14-8-4-5-9-15(14)25-17)19(24)22(20-12)13(2)18(23)21-10-6-3-7-11-21/h4-5,8-9,13H,3,6-7,10-11H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay					Assay Description The in vitro MKP-3 Phosphatase dose response hit/probe assessment assay has been developed and run at the University of Pittsburgh Molecular Screenin...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2H70D6B
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM35390 (2-(2-keto-1-methyl-2-piperidino-ethyl)-4-methyl-be...) Show SMILES CC(C(=O)N1CCCCC1)n1nc(C)c2sc3ccccc3c2c1=O Show InChI InChI=1S/C19H21N3O2S/c1-12-17-16(14-8-4-5-9-15(14)25-17)19(24)22(20-12)13(2)18(23)21-10-6-3-7-11-21/h4-5,8-9,13H,3,6-7,10-11H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay					Assay Description List of compounds to be tested: Compounds that met the active criterion of Z-score is				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2N58JS6
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM35390 (2-(2-keto-1-methyl-2-piperidino-ethyl)-4-methyl-be...) Show SMILES CC(C(=O)N1CCCCC1)n1nc(C)c2sc3ccccc3c2c1=O Show InChI InChI=1S/C19H21N3O2S/c1-12-17-16(14-8-4-5-9-15(14)25-17)19(24)22(20-12)13(2)18(23)21-10-6-3-7-11-21/h4-5,8-9,13H,3,6-7,10-11H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay					Assay Description List of compounds to be tested: Compounds that met the active criterion of Z-score is				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2T72FVT
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM35390 (2-(2-keto-1-methyl-2-piperidino-ethyl)-4-methyl-be...) Show SMILES CC(C(=O)N1CCCCC1)n1nc(C)c2sc3ccccc3c2c1=O Show InChI InChI=1S/C19H21N3O2S/c1-12-17-16(14-8-4-5-9-15(14)25-17)19(24)22(20-12)13(2)18(23)21-10-6-3-7-11-21/h4-5,8-9,13H,3,6-7,10-11H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay					Assay Description List of compounds to be tested: Compounds that met the active criterion of Z-score is				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2Z036KJ
					More data for this Ligand-Target Pair