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SMILES: COc1ccc(cc1)-n1c2nc(cnc2[nH]c1=O)-c1ccc(O)cc1

InChI Key: InChIKey=IWUITKREYZIEDR-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 354793   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human))	BDBM354793 (6-(4-hydroxyphenyl)-1-(4- methoxyphenyl)-1H- imida...) Show SMILES COc1ccc(cc1)-n1c2nc(cnc2[nH]c1=O)-c1ccc(O)cc1 Show InChI InChI=1S/C18H14N4O3/c1-25-14-8-4-12(5-9-14)22-17-16(21-18(22)24)19-10-15(20-17)11-2-6-13(23)7-3-11/h2-10,23H,1H3,(H,19,21,24)	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Rochester; Board of Regents of the University of Nebraska US Patent					Assay Description 200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...				US Patent US10485800 (2019) BindingDB Entry DOI: 10.7270/Q22B91DW
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human))	BDBM354793 (6-(4-hydroxyphenyl)-1-(4- methoxyphenyl)-1H- imida...) Show SMILES COc1ccc(cc1)-n1c2nc(cnc2[nH]c1=O)-c1ccc(O)cc1 Show InChI InChI=1S/C18H14N4O3/c1-25-14-8-4-12(5-9-14)22-17-16(21-18(22)24)19-10-15(20-17)11-2-6-13(23)7-3-11/h2-10,23H,1H3,(H,19,21,24)	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Rochester US Patent					Assay Description 200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...				US Patent US9814704 (2017) BindingDB Entry DOI: 10.7270/Q27H1MRN
					More data for this Ligand-Target Pair