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SMILES: Clc1cc(Cl)cc(c1)-c1cnc2[nH]c(=O)n(CC3CC3)c2n1

InChI Key: InChIKey=AFVQPMFFJNEQOI-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 354803   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human))	BDBM354803 (1-(cyclopropylmethyl)-6- (3,5-dichlorophenyl)-1H- ...) Show SMILES Clc1cc(Cl)cc(c1)-c1cnc2[nH]c(=O)n(CC3CC3)c2n1 Show InChI InChI=1S/C15H12Cl2N4O/c16-10-3-9(4-11(17)5-10)12-6-18-13-14(19-12)21(15(22)20-13)7-8-1-2-8/h3-6,8H,1-2,7H2,(H,18,20,22)	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Rochester; Board of Regents of the University of Nebraska US Patent					Assay Description 200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...				US Patent US10485800 (2019) BindingDB Entry DOI: 10.7270/Q22B91DW
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human))	BDBM354803 (1-(cyclopropylmethyl)-6- (3,5-dichlorophenyl)-1H- ...) Show SMILES Clc1cc(Cl)cc(c1)-c1cnc2[nH]c(=O)n(CC3CC3)c2n1 Show InChI InChI=1S/C15H12Cl2N4O/c16-10-3-9(4-11(17)5-10)12-6-18-13-14(19-12)21(15(22)20-13)7-8-1-2-8/h3-6,8H,1-2,7H2,(H,18,20,22)	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Rochester US Patent					Assay Description 200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...				US Patent US9814704 (2017) BindingDB Entry DOI: 10.7270/Q27H1MRN
					More data for this Ligand-Target Pair