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SMILES: NC(=O)c1ccc(cc1)-c1c[nH]c2ncc(cc12)-c1cccc(c1)C(=O)N1CC[NH2+]CC1

InChI Key: InChIKey=PRGMHVZMKYMIJG-UHFFFAOYSA-O

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 354875   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human))	BDBM354875 (Preparation of 4-{5-[3-(piperazine-1-carbonyl)-phe...) Show SMILES NC(=O)c1ccc(cc1)-c1c[nH]c2ncc(cc12)-c1cccc(c1)C(=O)N1CC[NH2+]CC1 Show InChI InChI=1S/C25H23N5O2/c26-23(31)17-6-4-16(5-7-17)22-15-29-24-21(22)13-20(14-28-24)18-2-1-3-19(12-18)25(32)30-10-8-27-9-11-30/h1-7,12-15,27H,8-11H2,(H2,26,31)(H,28,29)/p+1	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
The University of Rochester; Board of Regents of the University of Nebraska US Patent					Assay Description 200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...				US Patent US10485800 (2019) BindingDB Entry DOI: 10.7270/Q22B91DW
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human))	BDBM354875 (Preparation of 4-{5-[3-(piperazine-1-carbonyl)-phe...) Show SMILES NC(=O)c1ccc(cc1)-c1c[nH]c2ncc(cc12)-c1cccc(c1)C(=O)N1CC[NH2+]CC1 Show InChI InChI=1S/C25H23N5O2/c26-23(31)17-6-4-16(5-7-17)22-15-29-24-21(22)13-20(14-28-24)18-2-1-3-19(12-18)25(32)30-10-8-27-9-11-30/h1-7,12-15,27H,8-11H2,(H2,26,31)(H,28,29)/p+1	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
The University of Rochester US Patent					Assay Description 200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...				US Patent US9814704 (2017) BindingDB Entry DOI: 10.7270/Q27H1MRN
					More data for this Ligand-Target Pair