null

SMILES: CC(=O)N1CCN(CC1)C(=O)c1cccc(c1)-c1cnc2[nH]cc(-c3ccc(cc3)C(N)=O)c2c1

InChI Key: InChIKey=AJUHCVAZMDGWQB-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 354876   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human))	BDBM354876 (Preparation of 4-{5-[3-(4-acetyl-piperazine-1-carb...) Show SMILES CC(=O)N1CCN(CC1)C(=O)c1cccc(c1)-c1cnc2[nH]cc(-c3ccc(cc3)C(N)=O)c2c1 Show InChI InChI=1S/C27H25N5O3/c1-17(33)31-9-11-32(12-10-31)27(35)21-4-2-3-20(13-21)22-14-23-24(16-30-26(23)29-15-22)18-5-7-19(8-6-18)25(28)34/h2-8,13-16H,9-12H2,1H3,(H2,28,34)(H,29,30)	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
The University of Rochester; Board of Regents of the University of Nebraska US Patent					Assay Description 200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...				US Patent US10485800 (2019) BindingDB Entry DOI: 10.7270/Q22B91DW
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 11 (Homo sapiens (Human))	BDBM354876 (Preparation of 4-{5-[3-(4-acetyl-piperazine-1-carb...) Show SMILES CC(=O)N1CCN(CC1)C(=O)c1cccc(c1)-c1cnc2[nH]cc(-c3ccc(cc3)C(N)=O)c2c1 Show InChI InChI=1S/C27H25N5O3/c1-17(33)31-9-11-32(12-10-31)27(35)21-4-2-3-20(13-21)22-14-23-24(16-30-26(23)29-15-22)18-5-7-19(8-6-18)25(28)34/h2-8,13-16H,9-12H2,1H3,(H2,28,34)(H,29,30)	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
The University of Rochester US Patent					Assay Description 200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...				US Patent US9814704 (2017) BindingDB Entry DOI: 10.7270/Q27H1MRN
					More data for this Ligand-Target Pair