BDBM35489 1-Acetyl-3-(3,4-dichloro-5-oxo-2,5-dihydro-furan-2-yl)-urea::MLS000035450::N-[(3,4-dichloro-5-keto-2H-furan-2-yl)carbamoyl]acetamide::N-[(3,4-dichloro-5-oxo-2H-furan-2-yl)carbamoyl]acetamide::N-[[(3,4-dichloro-5-oxo-2H-furan-2-yl)amino]-oxomethyl]acetamide::N-[[3,4-bis(chloranyl)-5-oxidanylidene-2H-furan-2-yl]carbamoyl]ethanamide::SMR000001295::cid_654815

SMILES: CC(=O)NC(=O)NC1OC(=O)C(Cl)=C1Cl

InChI Key: InChIKey=NYALSNBKNBTFOV-UHFFFAOYSA-N

Data: 3 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 35489   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin B (Homo sapiens (Human))	BDBM35489 (1-Acetyl-3-(3,4-dichloro-5-oxo-2,5-dihydro-furan-2...) Show SMILES CC(=O)NC(=O)NC1OC(=O)C(Cl)=C1Cl |c:12| Show InChI InChI=1S/C7H6Cl2N2O4/c1-2(12)10-7(14)11-5-3(8)4(9)6(13)15-5/h5H,1H3,(H2,10,11,12,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	2.12E+3	n/a	n/a	n/a	n/a	6.8	23
PCMD Curated by PubChem BioAssay					Assay Description Screening Center: Penn Center for Molecular Discovery Center Affiliation: University of Pennsylvania Network: Molecular Library Screening Center Netw...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q25T3HTJ
					More data for this Ligand-Target Pair
Hsf1 protein (Mus musculus)	BDBM35489 (1-Acetyl-3-(3,4-dichloro-5-oxo-2,5-dihydro-furan-2...) Show SMILES CC(=O)NC(=O)NC1OC(=O)C(Cl)=C1Cl |c:12| Show InChI InChI=1S/C7H6Cl2N2O4/c1-2(12)10-7(14)11-5-3(8)4(9)6(13)15-5/h5H,1H3,(H2,10,11,12,14)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	>2.60E+5	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2P55KXK
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM35489 (1-Acetyl-3-(3,4-dichloro-5-oxo-2,5-dihydro-furan-2...) Show SMILES CC(=O)NC(=O)NC1OC(=O)C(Cl)=C1Cl |c:12| Show InChI InChI=1S/C7H6Cl2N2O4/c1-2(12)10-7(14)11-5-3(8)4(9)6(13)15-5/h5H,1H3,(H2,10,11,12,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
PCMD Curated by PubChem BioAssay					Assay Description Screening Center: Penn Center for Molecular Discovery Center Affiliation: University of Pennsylvania Network: Molecular Library Screening Center Netw...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2WH2NDV
					More data for this Ligand-Target Pair
Cathepsin B (Homo sapiens (Human))	BDBM35489 (1-Acetyl-3-(3,4-dichloro-5-oxo-2,5-dihydro-furan-2...) Show SMILES CC(=O)NC(=O)NC1OC(=O)C(Cl)=C1Cl |c:12| Show InChI InChI=1S/C7H6Cl2N2O4/c1-2(12)10-7(14)11-5-3(8)4(9)6(13)15-5/h5H,1H3,(H2,10,11,12,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	2.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
PCMD Curated by PubChem BioAssay					Assay Description Screening Center: Penn Center for Molecular Discovery Center Affiliation: University of Pennsylvania Network: Molecular Library Screening Center Netw...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2C53J7N
					More data for this Ligand-Target Pair