BDBM356624 US10214478, Compound NM-008

SMILES: NC12CC3CC(CO[N+]([O-])=O)(C1)CC(CO[N+]([O-])=O)(C3)C2

InChI Key: InChIKey=PHNDBLVSIRMDAO-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 356624   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM356624 (US10214478, Compound NM-008) Show SMILES NC12CC3CC(CO[N+]([O-])=O)(C1)CC(CO[N+]([O-])=O)(C3)C2 |TLB:11:1:19:5.4.12,4:5:20:19.3.2,4:3:20:5.11.12,6:5:19:20.1.2,THB:11:5:19:20.1.2| Show InChI InChI=1S/C12H19N3O6/c13-12-3-9-1-10(5-12,7-20-14(16)17)4-11(2-9,6-12)8-21-15(18)19/h9H,1-8,13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	4.37E+3	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Isolated primary cerebellum granule cells of infant rats were inoculated in 96-well plates with 1.2×105/well by using 10% FBS+25 mM KCl+2 mM Glutamin...				US Patent US10214478 (2019) BindingDB Entry DOI: 10.7270/Q2V12745
					More data for this Ligand-Target Pair