BDBM356631 Nitromemantine::US10214478, Compound YQW-036

SMILES: CCC12CC3(N)CC(CC)(C1)CC(C3)(C2)O[N+]([O-])=O

InChI Key: InChIKey=SENUTBBWBZZNRT-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 356631   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM356631 (Nitromemantine | US10214478, Compound YQW-036) Show SMILES CCC12CC3(N)CC(CC)(C1)CC(C3)(C2)O[N+]([O-])=O |TLB:8:7:3.4.13:14,6:7:3.4.13:14,6:4:11.7.10:14,5:4:11:10.2.14,THB:3:2:11:4.13.6,3:4:11:10.2.14| Show InChI InChI=1S/C14H24N2O3/c1-3-11-5-12(4-2)7-13(15,6-11)10-14(8-11,9-12)19-16(17)18/h3-10,15H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.14E+4	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Isolated primary cerebellum granule cells of infant rats were inoculated in 96-well plates with 1.2×105/well by using 10% FBS+25 mM KCl+2 mM Glutamin...				US Patent US10214478 (2019) BindingDB Entry DOI: 10.7270/Q2V12745
					More data for this Ligand-Target Pair