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SMILES: CC(C)N1CCCN(CC(C)(O)Cn2c3ccc(F)cc3c3cc(F)ccc23)C1=O

InChI Key: InChIKey=BOIUIFIXELNTMB-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 356659   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM356659 (1-(3-(3,6-difluoro- 9H-carbazol-9-yl)-2- hydroxy-2...) Show SMILES CC(C)N1CCCN(CC(C)(O)Cn2c3ccc(F)cc3c3cc(F)ccc23)C1=O Show InChI InChI=1S/C23H27F2N3O2/c1-15(2)27-10-4-9-26(22(27)29)13-23(3,30)14-28-20-7-5-16(24)11-18(20)19-12-17(25)6-8-21(19)28/h5-8,11-12,15,30H,4,9-10,13-14H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.11E+3	n/a	n/a	n/a	n/a
Synchronicity Pharma, Inc. US Patent					Assay Description In brief, stable U20S reporter cells harboring Per2-dLuc were plated at a density of 30,000 cells/well in Corning 96-well, solid white, flat bottom, ...				US Patent US10759777 (2020)
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM356659 (1-(3-(3,6-difluoro- 9H-carbazol-9-yl)-2- hydroxy-2...) Show SMILES CC(C)N1CCCN(CC(C)(O)Cn2c3ccc(F)cc3c3cc(F)ccc23)C1=O Show InChI InChI=1S/C23H27F2N3O2/c1-15(2)27-10-4-9-26(22(27)29)13-23(3,30)14-28-20-7-5-16(24)11-18(20)19-12-17(25)6-8-21(19)28/h5-8,11-12,15,30H,4,9-10,13-14H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.11E+3	n/a	n/a	n/a	n/a
Reset Therapeutics, Inc. US Patent					Assay Description Compounds were screened by using a high-throughput circadian assay system as previously described in Zhang, E. E. et al. Cell, 2009, 139, 199-210. In...				US Patent US10214507 (2019) BindingDB Entry DOI: 10.7270/Q2KH0QMT
					More data for this Ligand-Target Pair