BDBM356695 1-cyclobutyl-3-(3- (3,6-difluoro-9H- carbazol-9-yl)-2- hydroxypropyl)imid- azolidin-2-one::US10214507, Compound 93::US10759777, Compound 93

SMILES: OC(CN1CCN(C2CCC2)C1=O)Cn1c2ccc(F)cc2c2cc(F)ccc12

InChI Key: InChIKey=KVSLXAKIFPQUMO-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 356695   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM356695 (1-cyclobutyl-3-(3- (3,6-difluoro-9H- carbazol-9-yl...) Show SMILES OC(CN1CCN(C2CCC2)C1=O)Cn1c2ccc(F)cc2c2cc(F)ccc12 Show InChI InChI=1S/C22H23F2N3O2/c23-14-4-6-20-18(10-14)19-11-15(24)5-7-21(19)27(20)13-17(28)12-25-8-9-26(22(25)29)16-2-1-3-16/h4-7,10-11,16-17,28H,1-3,8-9,12-13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	129	n/a	n/a	n/a	n/a
Synchronicity Pharma, Inc. US Patent					Assay Description In brief, stable U20S reporter cells harboring Per2-dLuc were plated at a density of 30,000 cells/well in Corning 96-well, solid white, flat bottom, ...				US Patent US10759777 (2020)
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM356695 (1-cyclobutyl-3-(3- (3,6-difluoro-9H- carbazol-9-yl...) Show SMILES OC(CN1CCN(C2CCC2)C1=O)Cn1c2ccc(F)cc2c2cc(F)ccc12 Show InChI InChI=1S/C22H23F2N3O2/c23-14-4-6-20-18(10-14)19-11-15(24)5-7-21(19)27(20)13-17(28)12-25-8-9-26(22(25)29)16-2-1-3-16/h4-7,10-11,16-17,28H,1-3,8-9,12-13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	129	n/a	n/a	n/a	n/a
Reset Therapeutics, Inc. US Patent					Assay Description Compounds were screened by using a high-throughput circadian assay system as previously described in Zhang, E. E. et al. Cell, 2009, 139, 199-210. In...				US Patent US10214507 (2019) BindingDB Entry DOI: 10.7270/Q2KH0QMT
					More data for this Ligand-Target Pair