null

SMILES: CC1CCC(=O)N(CC(C)(O)Cn2c3ccc(F)cc3c3cc(F)ccc23)C1

InChI Key: InChIKey=HVWAMXABQUFNDR-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 356723   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM356723 (1-(3-(3,6-difluoro- 9H-carbazol-9-yl)-2- hydroxy-2...) Show SMILES CC1CCC(=O)N(CC(C)(O)Cn2c3ccc(F)cc3c3cc(F)ccc23)C1 Show InChI InChI=1S/C22H24F2N2O2/c1-14-3-8-21(27)25(11-14)12-22(2,28)13-26-19-6-4-15(23)9-17(19)18-10-16(24)5-7-20(18)26/h4-7,9-10,14,28H,3,8,11-13H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.22E+3	n/a	n/a	n/a	n/a
Synchronicity Pharma, Inc. US Patent					Assay Description In brief, stable U20S reporter cells harboring Per2-dLuc were plated at a density of 30,000 cells/well in Corning 96-well, solid white, flat bottom, ...				US Patent US10759777 (2020)
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM356723 (1-(3-(3,6-difluoro- 9H-carbazol-9-yl)-2- hydroxy-2...) Show SMILES CC1CCC(=O)N(CC(C)(O)Cn2c3ccc(F)cc3c3cc(F)ccc23)C1 Show InChI InChI=1S/C22H24F2N2O2/c1-14-3-8-21(27)25(11-14)12-22(2,28)13-26-19-6-4-15(23)9-17(19)18-10-16(24)5-7-20(18)26/h4-7,9-10,14,28H,3,8,11-13H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.22E+3	n/a	n/a	n/a	n/a
Reset Therapeutics, Inc. US Patent					Assay Description Compounds were screened by using a high-throughput circadian assay system as previously described in Zhang, E. E. et al. Cell, 2009, 139, 199-210. In...				US Patent US10214507 (2019) BindingDB Entry DOI: 10.7270/Q2KH0QMT
					More data for this Ligand-Target Pair