null

SMILES: CC(O)(CN1CCC(F)(F)C1=O)Cn1c2ccc(F)cc2c2cc(F)ccc12

InChI Key: InChIKey=KWPKBCIYVSGRNL-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 356961   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM356961 (1-(3-(3,6-difluoro- 9H-carbazol-9-yl)-2- hydroxy-2...) Show SMILES CC(O)(CN1CCC(F)(F)C1=O)Cn1c2ccc(F)cc2c2cc(F)ccc12 Show InChI InChI=1S/C20H18F4N2O2/c1-19(28,10-25-7-6-20(23,24)18(25)27)11-26-16-4-2-12(21)8-14(16)15-9-13(22)3-5-17(15)26/h2-5,8-9,28H,6-7,10-11H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	986	n/a	n/a	n/a	n/a
Synchronicity Pharma, Inc. US Patent					Assay Description In brief, stable U20S reporter cells harboring Per2-dLuc were plated at a density of 30,000 cells/well in Corning 96-well, solid white, flat bottom, ...				US Patent US10759777 (2020)
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM356961 (1-(3-(3,6-difluoro- 9H-carbazol-9-yl)-2- hydroxy-2...) Show SMILES CC(O)(CN1CCC(F)(F)C1=O)Cn1c2ccc(F)cc2c2cc(F)ccc12 Show InChI InChI=1S/C20H18F4N2O2/c1-19(28,10-25-7-6-20(23,24)18(25)27)11-26-16-4-2-12(21)8-14(16)15-9-13(22)3-5-17(15)26/h2-5,8-9,28H,6-7,10-11H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	986	n/a	n/a	n/a	n/a
Reset Therapeutics, Inc. US Patent					Assay Description Compounds were screened by using a high-throughput circadian assay system as previously described in Zhang, E. E. et al. Cell, 2009, 139, 199-210. In...				US Patent US10214507 (2019) BindingDB Entry DOI: 10.7270/Q2KH0QMT
					More data for this Ligand-Target Pair