BDBM357642 7-((3'-fluoro- [1,1'- biphenyl]-3- yl) methyl)- 3H- [1,2,3]triazolo [4,5-b] pyridin- 5-amine::US10214527, Example 14

SMILES: Nc1cc(Cc2cccc(c2)-c2cccc(F)c2)c2nn[nH]c2n1

InChI Key: InChIKey=CBCXLSJDXOMJRA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 357642   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Myeloperoxidase (Homo sapiens (Human))	BDBM357642 (7-((3'-fluoro- [1,1'- biphenyl]-3- yl) methyl)- 3H...) Show SMILES Nc1cc(Cc2cccc(c2)-c2cccc(F)c2)c2nn[nH]c2n1 Show InChI InChI=1S/C18H14FN5/c19-15-6-2-5-13(9-15)12-4-1-3-11(7-12)8-14-10-16(20)21-18-17(14)22-24-23-18/h1-7,9-10H,8H2,(H3,20,21,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description MPO peroxidation activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Amplex Red (Invitrogen catalog # A12222) which...				US Patent US10214527 (2019) BindingDB Entry DOI: 10.7270/Q2DR2XRQ
					More data for this Ligand-Target Pair
Myeloperoxidase (Homo sapiens (Human))	BDBM357642 (7-((3'-fluoro- [1,1'- biphenyl]-3- yl) methyl)- 3H...) Show SMILES Nc1cc(Cc2cccc(c2)-c2cccc(F)c2)c2nn[nH]c2n1 Show InChI InChI=1S/C18H14FN5/c19-15-6-2-5-13(9-15)12-4-1-3-11(7-12)8-14-10-16(20)21-18-17(14)22-24-23-18/h1-7,9-10H,8H2,(H3,20,21,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description MPO chlorination activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Aminophenyl fluorescein (APF, Invitrogen catal...				US Patent US10214527 (2019) BindingDB Entry DOI: 10.7270/Q2DR2XRQ
					More data for this Ligand-Target Pair