null

SMILES: Nc1cc(Cc2cccc(Cc3ccccc3)c2)c2nn[nH]c2n1

InChI Key: InChIKey=QAYFAZVYHUBONM-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 357644   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Myeloperoxidase (Homo sapiens (Human))	BDBM357644 (7-(3- benzylbenzyl)- 3H- [1,2,3]triazolo [4,5-b]py...) Show SMILES Nc1cc(Cc2cccc(Cc3ccccc3)c2)c2nn[nH]c2n1 Show InChI InChI=1S/C19H17N5/c20-17-12-16(18-19(21-17)23-24-22-18)11-15-8-4-7-14(10-15)9-13-5-2-1-3-6-13/h1-8,10,12H,9,11H2,(H3,20,21,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description MPO peroxidation activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Amplex Red (Invitrogen catalog # A12222) which...				US Patent US10214527 (2019) BindingDB Entry DOI: 10.7270/Q2DR2XRQ
					More data for this Ligand-Target Pair
Myeloperoxidase (Homo sapiens (Human))	BDBM357644 (7-(3- benzylbenzyl)- 3H- [1,2,3]triazolo [4,5-b]py...) Show SMILES Nc1cc(Cc2cccc(Cc3ccccc3)c2)c2nn[nH]c2n1 Show InChI InChI=1S/C19H17N5/c20-17-12-16(18-19(21-17)23-24-22-18)11-15-8-4-7-14(10-15)9-13-5-2-1-3-6-13/h1-8,10,12H,9,11H2,(H3,20,21,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description MPO chlorination activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Aminophenyl fluorescein (APF, Invitrogen catal...				US Patent US10214527 (2019) BindingDB Entry DOI: 10.7270/Q2DR2XRQ
					More data for this Ligand-Target Pair