BDBM357667 (4-((5-amino- 3H- [1,2,3]triazolo [4,5-b] pyridin- 7- yl)methyl) phenyl)(phenyl) methanone::US10214527, Example 39

SMILES: Nc1cc(Cc2ccc(cc2)C(=O)c2ccccc2)c2nn[nH]c2n1

InChI Key: InChIKey=NFQAUMODIRAOSU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 357667   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Myeloperoxidase (Homo sapiens (Human))	BDBM357667 ((4-((5-amino- 3H- [1,2,3]triazolo [4,5-b] pyridin-...) Show SMILES Nc1cc(Cc2ccc(cc2)C(=O)c2ccccc2)c2nn[nH]c2n1 Show InChI InChI=1S/C19H15N5O/c20-16-11-15(17-19(21-16)23-24-22-17)10-12-6-8-14(9-7-12)18(25)13-4-2-1-3-5-13/h1-9,11H,10H2,(H3,20,21,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description MPO peroxidation activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Amplex Red (Invitrogen catalog # A12222) which...				US Patent US10214527 (2019) BindingDB Entry DOI: 10.7270/Q2DR2XRQ
					More data for this Ligand-Target Pair