null
SMILES: Nc1cc(Cc2cccc(c2)C(=O)c2ccccc2)c2nn[nH]c2n1
InChI Key: InChIKey=IMKJUMVUMWNOTC-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Myeloperoxidase (Homo sapiens (Human)) | BDBM357668 ((3-((5-amino- 3H- [1,2,3]triazolo [4,5-b] pyridin-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description MPO peroxidation activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Amplex Red (Invitrogen catalog # A12222) which... | US Patent US10214527 (2019) BindingDB Entry DOI: 10.7270/Q2DR2XRQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Myeloperoxidase (Homo sapiens (Human)) | BDBM357668 ((3-((5-amino- 3H- [1,2,3]triazolo [4,5-b] pyridin-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description MPO chlorination activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Aminophenyl fluorescein (APF, Invitrogen catal... | US Patent US10214527 (2019) BindingDB Entry DOI: 10.7270/Q2DR2XRQ | |||||||||||
More data for this Ligand-Target Pair |