BDBM357672 7-(2,3- difluorobenzyl)- 3H-[1,2,3] triazolo[4,5- b]pyridin-5- amine::US10214527, Example 44

SMILES: Nc1cc(Cc2cccc(F)c2F)c2nn[nH]c2n1

InChI Key: InChIKey=WVALIXNAYAODCE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 357672   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Myeloperoxidase (Homo sapiens (Human))	BDBM357672 (7-(2,3- difluorobenzyl)- 3H-[1,2,3] triazolo[4,5- ...) Show SMILES Nc1cc(Cc2cccc(F)c2F)c2nn[nH]c2n1 Show InChI InChI=1S/C12H9F2N5/c13-8-3-1-2-6(10(8)14)4-7-5-9(15)16-12-11(7)17-19-18-12/h1-3,5H,4H2,(H3,15,16,17,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description MPO peroxidation activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Amplex Red (Invitrogen catalog # A12222) which...				US Patent US10214527 (2019) BindingDB Entry DOI: 10.7270/Q2DR2XRQ
					More data for this Ligand-Target Pair
Myeloperoxidase (Homo sapiens (Human))	BDBM357672 (7-(2,3- difluorobenzyl)- 3H-[1,2,3] triazolo[4,5- ...) Show SMILES Nc1cc(Cc2cccc(F)c2F)c2nn[nH]c2n1 Show InChI InChI=1S/C12H9F2N5/c13-8-3-1-2-6(10(8)14)4-7-5-9(15)16-12-11(7)17-19-18-12/h1-3,5H,4H2,(H3,15,16,17,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description MPO chlorination activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Aminophenyl fluorescein (APF, Invitrogen catal...				US Patent US10214527 (2019) BindingDB Entry DOI: 10.7270/Q2DR2XRQ
					More data for this Ligand-Target Pair