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SMILES: Nc1nc2oc3cnc(cc3c(=O)c2cc1C(O)=O)C1=CCCCC1

InChI Key: InChIKey=NEEUDSQELOSEMY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 357900   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase TBK1


(Homo sapiens (Human))		BDBM357900
PNG
(US10214536, Compound 176)
Show SMILES Nc1nc2oc3cnc(cc3c(=O)c2cc1C(O)=O)C1=CCCCC1 |t:22|
Show InChI InChI=1S/C18H15N3O4/c19-16-12(18(23)24)6-11-15(22)10-7-13(9-4-2-1-3-5-9)20-8-14(10)25-17(11)21-16/h4,6-8H,1-3,5H2,(H2,19,21)(H,23,24)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/a 1.40E+3n/an/an/an/an/an/a



THE REGENTS OF THE UNIVERSITY OF MICHIGAN

US Patent


Assay Description
Kinase assays are commonly used for determining the ability of a small molecule to inhibit enzyme activity. By measuring the degree of phosphorylatio...

US Patent US10214536 (2019)


BindingDB Entry DOI: 10.7270/Q2N87D2S
More data for this
Ligand-Target Pair