BDBM357911 2-Amino-8-cyclohexyl-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid::US10214536, Compound 260

SMILES: Nc1nc2oc3cc(ccc3c(=O)c2cc1C(O)=O)C1CCCCC1

InChI Key: InChIKey=GZYNTHMFEOIQMO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 357911   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein cereblon/Serine/threonine-protein kinase TBK1 (Homo sapiens (Human))	BDBM357911 (2-Amino-8-cyclohexyl-5-oxo-5H-chromeno[2,3-b]pyrid...) Show SMILES Nc1nc2oc3cc(ccc3c(=O)c2cc1C(O)=O)C1CCCCC1 Show InChI InChI=1S/C19H18N2O4/c20-17-14(19(23)24)9-13-16(22)12-7-6-11(10-4-2-1-3-5-10)8-15(12)25-18(13)21-17/h6-10H,1-5H2,(H2,20,21)(H,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent					Assay Description Kinase assays are commonly used for determining the ability of a small molecule to inhibit enzyme activity. By measuring the degree of phosphorylatio...				US Patent US10214536 (2019) BindingDB Entry DOI: 10.7270/Q2N87D2S
					More data for this Ligand-Target Pair