null
SMILES: CC(C)c1ccc2oc3nc(N)c(cc3c(=O)c2c1)C(=O)Nc1nnn[nH]1
InChI Key: InChIKey=JDIHMNISRGRMDY-UHFFFAOYSA-N
PDB links: 1 PDB ID matches this monomer.
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serine/threonine-protein kinase TBK1 (Homo sapiens (Human)) | BDBM357921 (US10214536, Compound 288) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB US Patent | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent | Assay Description Kinase assays are commonly used for determining the ability of a small molecule to inhibit enzyme activity. By measuring the degree of phosphorylatio... | US Patent US10214536 (2019) BindingDB Entry DOI: 10.7270/Q2N87D2S | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |