BDBM3581 8-[(3-Bromophenyl)amino]-1H-pyrazolo[3,4-g]quinazoline::N-(3-bromophenyl)-1H-pyrazolo[3,4-g]quinazolin-8-amine::Pyrazoloquinazoline deriv. 19

SMILES: Brc1cccc(Nc2ncnc3cc4cn[nH]c4cc23)c1

InChI Key: InChIKey=PKYIIOKOAUBHMM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3581   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM3581 (8-[(3-Bromophenyl)amino]-1H-pyrazolo[3,4-g]quinazo...) Show SMILES Brc1cccc(Nc2ncnc3cc4cn[nH]c4cc23)c1 Show InChI InChI=1S/C15H10BrN5/c16-10-2-1-3-11(5-10)20-15-12-6-13-9(7-19-21-13)4-14(12)17-8-18-15/h1-8H,(H,19,21)(H,17,18,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.340	n/a	n/a	n/a	n/a	7.4	22
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 39: 918-28 (1996) Article DOI: 10.1021/jm950692f BindingDB Entry DOI: 10.7270/Q2222RZB
					More data for this Ligand-Target Pair