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BDBM358610 (R)-2-(4-acetyl-3-ethyl-3-methyl-2- oxopiperazin-1-yl)-4-(4-amino-5- chloropyrrolo[2,1-f][1,2,4]triazin-7- yl)benzonitrile::US10214537, Example 687

SMILES:

InChI Key:

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 358610   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform/gamma isoform


(Homo sapiens (Human))
BDBM358610
PNG
((R)-2-(4-acetyl-3-ethyl-3-methyl-2- oxopiperazin-1...)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.200n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent




US Patent US10214537 (2019)

More data for this
Ligand-Target Pair