BDBM35890 flufenamic acid analogue, 17

SMILES: CCCCCCOc1ccc(Nc2ccccc2C(O)=O)cc1

InChI Key: InChIKey=JKZQPQIMGVHZRH-UHFFFAOYSA-N

Data: 1 IC50

PDB links: 1 PDB ID contains this monomer as substructures. 1 PDB ID contains inhibitors having a similarity of 90% to this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 35890   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen Receptor (Homo sapiens (Human))	BDBM35890 (flufenamic acid analogue, 17) Show SMILES CCCCCCOc1ccc(Nc2ccccc2C(O)=O)cc1 Show InChI InChI=1S/C19H23NO3/c1-2-3-4-7-14-23-16-12-10-15(11-13-16)20-18-9-6-5-8-17(18)19(21)22/h5-6,8-13,20H,2-4,7,14H2,1H3,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	7.2	23
St. Jude Research Hospital					Assay Description A radiolabeled ligand competition scintillation proximity assay (SPA) for the androgen receptor (AR) using Ni-coated 384-well FlashPlates. It measure...				ACS Chem Biol 4: 834-43 (2009) Article DOI: 10.1021/cb900143a BindingDB Entry DOI: 10.7270/Q2V986DC
					More data for this Ligand-Target Pair