BDBM359236 US10221129, Example JB-46

SMILES: COc1ccc(cc1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)NS(=O)(=O)Nc1cc(F)cc(F)c1

InChI Key: InChIKey=HIOKUPJYXPHXNF-QFIPXVFZSA-N

Data: 1 EC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 359236   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Envelope glycoprotein gp160 (Human immunodeficiency virus type 1 (isolate BRU/L...)	BDBM359236 (US10221129, Example JB-46) Show SMILES COc1ccc(cc1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)NS(=O)(=O)Nc1cc(F)cc(F)c1 |r| Show InChI InChI=1S/C24H24F2N4O5S/c1-30(20-8-10-21(35-2)11-9-20)23(31)22(12-16-6-4-3-5-7-16)27-24(32)29-36(33,34)28-19-14-17(25)13-18(26)15-19/h3-11,13-15,22,28H,12H2,1-2H3,(H2,27,29,32)/t22-/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	80	n/a	n/a	n/a	n/a
VIIV HEALTHCARE UK (NO.5) LIMITED US Patent					Assay Description HIV cell culture assay-MT-2 cells, 293T cells and the proviral DNA clone of NL4-3 virus were obtained from the NIH AIDS Research and Reference Reagen...				US Patent US10221129 (2019) BindingDB Entry DOI: 10.7270/Q2R213N8
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