BDBM359853 US9822120, Compound 7

SMILES: Cc1ncc(COc2cc(F)cc(Oc3ccc(cc3)-c3nc(C4CCOCC4)n4ccnc(N)c34)c2)s1

InChI Key: InChIKey=GKRUOHSOTFNKIJ-UHFFFAOYSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 359853   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM359853 (US9822120, Compound 7) Show SMILES Cc1ncc(COc2cc(F)cc(Oc3ccc(cc3)-c3nc(C4CCOCC4)n4ccnc(N)c34)c2)s1 Show InChI InChI=1S/C28H26FN5O3S/c1-17-32-15-24(38-17)16-36-22-12-20(29)13-23(14-22)37-21-4-2-18(3-5-21)25-26-27(30)31-8-9-34(26)28(33-25)19-6-10-35-11-7-19/h2-5,8-9,12-15,19H,6-7,10-11,16H2,1H3,(H2,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmascience Inc. US Patent					Assay Description Method A: Fluorescence polarization-based kinase assays were performed in 384 well-plate format using histidine tagged recombinant human full-length ...				US Patent US9822120 (2017) BindingDB Entry DOI: 10.7270/Q2639S1W
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM359853 (US9822120, Compound 7) Show SMILES Cc1ncc(COc2cc(F)cc(Oc3ccc(cc3)-c3nc(C4CCOCC4)n4ccnc(N)c34)c2)s1 Show InChI InChI=1S/C28H26FN5O3S/c1-17-32-15-24(38-17)16-36-22-12-20(29)13-23(14-22)37-21-4-2-18(3-5-21)25-26-27(30)31-8-9-34(26)28(33-25)19-6-10-35-11-7-19/h2-5,8-9,12-15,19H,6-7,10-11,16H2,1H3,(H2,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a
Pharmascience Inc. US Patent					Assay Description Method A: Fluorescence polarization-based kinase assays were performed in 384 well-plate format using histidine tagged recombinant human full-length ...				US Patent US9822120 (2017) BindingDB Entry DOI: 10.7270/Q2639S1W
					More data for this Ligand-Target Pair