BDBM359863 US9822120, Compound 17

SMILES: Cc1ncc(COc2cc(F)cc(Oc3ccc(cc3)-c3nc(C4CC(=O)C4)n4ccnc(N)c34)c2)s1

InChI Key: InChIKey=HYQANEIQGZPKKD-UHFFFAOYSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 359863   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM359863 (US9822120, Compound 17) Show SMILES Cc1ncc(COc2cc(F)cc(Oc3ccc(cc3)-c3nc(C4CC(=O)C4)n4ccnc(N)c34)c2)s1 Show InChI InChI=1S/C27H22FN5O3S/c1-15-31-13-23(37-15)14-35-21-10-18(28)11-22(12-21)36-20-4-2-16(3-5-20)24-25-26(29)30-6-7-33(25)27(32-24)17-8-19(34)9-17/h2-7,10-13,17H,8-9,14H2,1H3,(H2,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmascience Inc. US Patent					Assay Description Method A: Fluorescence polarization-based kinase assays were performed in 384 well-plate format using histidine tagged recombinant human full-length ...				US Patent US9822120 (2017) BindingDB Entry DOI: 10.7270/Q2639S1W
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM359863 (US9822120, Compound 17) Show SMILES Cc1ncc(COc2cc(F)cc(Oc3ccc(cc3)-c3nc(C4CC(=O)C4)n4ccnc(N)c34)c2)s1 Show InChI InChI=1S/C27H22FN5O3S/c1-15-31-13-23(37-15)14-35-21-10-18(28)11-22(12-21)36-20-4-2-16(3-5-20)24-25-26(29)30-6-7-33(25)27(32-24)17-8-19(34)9-17/h2-7,10-13,17H,8-9,14H2,1H3,(H2,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a
Pharmascience Inc. US Patent					Assay Description Method A: Fluorescence polarization-based kinase assays were performed in 384 well-plate format using histidine tagged recombinant human full-length ...				US Patent US9822120 (2017) BindingDB Entry DOI: 10.7270/Q2639S1W
					More data for this Ligand-Target Pair