BDBM360667 US9828381, 1-6

SMILES: Cc1cc(N2CCC[C@H](O)C2)n2nc(Cc3ccc(Cl)cc3)cc2n1

InChI Key: InChIKey=ZXWQLXNWRSWVAN-KRWDZBQOSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 360667   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GABA B receptor (Rattus norvegicus)	BDBM360667 (US9828381, 1-6) Show SMILES Cc1cc(N2CCC[C@H](O)C2)n2nc(Cc3ccc(Cl)cc3)cc2n1 Show InChI InChI=1S/C19H21ClN4O/c1-13-9-19(23-8-2-3-17(25)12-23)24-18(21-13)11-16(22-24)10-14-4-6-15(20)7-5-14/h4-7,9,11,17,25H,2-3,8,10,12H2,1H3/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	974	n/a	n/a	n/a	n/a
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent					Assay Description The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...				US Patent US9828381 (2017) BindingDB Entry DOI: 10.7270/Q21C205Q
					More data for this Ligand-Target Pair