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BDBM360735 US9828381, 8-20

SMILES: CC(c1cc2nc(C)cc(NC3CC(F)(F)C3)n2n1)c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=RWMIHSNMNWESSM-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 360735   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
GABA B receptor


(Rattus norvegicus)		BDBM360735
PNG
(US9828381, 8-20)
Show SMILES CC(c1cc2nc(C)cc(NC3CC(F)(F)C3)n2n1)c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C20H19F5N4/c1-11-7-17(27-15-9-19(21,22)10-15)29-18(26-11)8-16(28-29)12(2)13-3-5-14(6-4-13)20(23,24)25/h3-8,12,15,27H,9-10H2,1-2H3
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PC cid
PC sid
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US Patent
n/an/an/an/a 500n/an/an/an/a



AbbVie Deutschland GmbH & Co. KG; AbbVie Inc.

US Patent


Assay Description
The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...

US Patent US9828381 (2017)


BindingDB Entry DOI: 10.7270/Q21C205Q
More data for this
Ligand-Target Pair