BDBM361128 (R)-4-(2-amino-7- methyl-1H- benzo[d]imidazol-4-yl)- N1-(pyrrolidin-3-yl)-3- (2H-tetrazol-5- yl)benzene-1,2- disulfonamide::US10221163, Example 285::US10544130, Example 285

SMILES: Cc1ccc(-c2ccc(c(c2-c2nn[nH]n2)S(N)(=O)=O)S(=O)(=O)N[C@@H]2CCNC2)c2nc(N)[nH]c12

InChI Key: InChIKey=XNKOFTAOJRCAMQ-PJSNMCHCSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 361128   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM361128 ((R)-4-(2-amino-7- methyl-1H- benzo[d]imidazol-4-yl...) Show SMILES Cc1ccc(-c2ccc(c(c2-c2nn[nH]n2)S(N)(=O)=O)S(=O)(=O)N[C@@H]2CCNC2)c2nc(N)[nH]c12 |r| Show InChI InChI=1S/C19H20N10O4S2/c1-9-2-3-12(16-15(9)23-19(20)24-16)11-4-5-13(35(32,33)27-10-6-7-22-8-10)17(34(21,30)31)14(11)18-25-28-29-26-18/h2-5,10,22,27H,6-8H2,1H3,(H2,20,23)(H2,21,30,31)/b12-11+/t10-/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.318	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10221163 (2019) BindingDB Entry DOI: 10.7270/Q2RX9FB1
					More data for this Ligand-Target Pair
Beta-lactamase NDM-1 (Klebsiella pneumoniae)	BDBM361128 ((R)-4-(2-amino-7- methyl-1H- benzo[d]imidazol-4-yl...) Show SMILES Cc1ccc(-c2ccc(c(c2-c2nn[nH]n2)S(N)(=O)=O)S(=O)(=O)N[C@@H]2CCNC2)c2nc(N)[nH]c12 |r| Show InChI InChI=1S/C19H20N10O4S2/c1-9-2-3-12(16-15(9)23-19(20)24-16)11-4-5-13(35(32,33)27-10-6-7-22-8-10)17(34(21,30)31)14(11)18-25-28-29-26-18/h2-5,10,22,27H,6-8H2,1H3,(H2,20,23)(H2,21,30,31)/b12-11+/t10-/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0300	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10221163 (2019) BindingDB Entry DOI: 10.7270/Q2RX9FB1
					More data for this Ligand-Target Pair
Beta-lactamase ()	BDBM361128 ((R)-4-(2-amino-7- methyl-1H- benzo[d]imidazol-4-yl...) Show SMILES Cc1ccc(-c2ccc(c(c2-c2nn[nH]n2)S(N)(=O)=O)S(=O)(=O)N[C@@H]2CCNC2)c2nc(N)[nH]c12 |r| Show InChI InChI=1S/C19H20N10O4S2/c1-9-2-3-12(16-15(9)23-19(20)24-16)11-4-5-13(35(32,33)27-10-6-7-22-8-10)17(34(21,30)31)14(11)18-25-28-29-26-18/h2-5,10,22,27H,6-8H2,1H3,(H2,20,23)(H2,21,30,31)/b12-11+/t10-/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0920	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent									US Patent US10544130 (2020) BindingDB Entry DOI: 10.7270/Q2C82CQH
					More data for this Ligand-Target Pair
Metallo-beta-lactamase type 2 (Serratia marcescens)	BDBM361128 ((R)-4-(2-amino-7- methyl-1H- benzo[d]imidazol-4-yl...) Show SMILES Cc1ccc(-c2ccc(c(c2-c2nn[nH]n2)S(N)(=O)=O)S(=O)(=O)N[C@@H]2CCNC2)c2nc(N)[nH]c12 |r| Show InChI InChI=1S/C19H20N10O4S2/c1-9-2-3-12(16-15(9)23-19(20)24-16)11-4-5-13(35(32,33)27-10-6-7-22-8-10)17(34(21,30)31)14(11)18-25-28-29-26-18/h2-5,10,22,27H,6-8H2,1H3,(H2,20,23)(H2,21,30,31)/b12-11+/t10-/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.318	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10544130 (2020) BindingDB Entry DOI: 10.7270/Q2C82CQH
					More data for this Ligand-Target Pair
Beta-lactamase NDM-1 (Klebsiella pneumoniae)	BDBM361128 ((R)-4-(2-amino-7- methyl-1H- benzo[d]imidazol-4-yl...) Show SMILES Cc1ccc(-c2ccc(c(c2-c2nn[nH]n2)S(N)(=O)=O)S(=O)(=O)N[C@@H]2CCNC2)c2nc(N)[nH]c12 |r| Show InChI InChI=1S/C19H20N10O4S2/c1-9-2-3-12(16-15(9)23-19(20)24-16)11-4-5-13(35(32,33)27-10-6-7-22-8-10)17(34(21,30)31)14(11)18-25-28-29-26-18/h2-5,10,22,27H,6-8H2,1H3,(H2,20,23)(H2,21,30,31)/b12-11+/t10-/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0300	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent									US Patent US10544130 (2020) BindingDB Entry DOI: 10.7270/Q2C82CQH
					More data for this Ligand-Target Pair
Beta-lactamase VIM-1 (Klebsiella pneumoniae)	BDBM361128 ((R)-4-(2-amino-7- methyl-1H- benzo[d]imidazol-4-yl...) Show SMILES Cc1ccc(-c2ccc(c(c2-c2nn[nH]n2)S(N)(=O)=O)S(=O)(=O)N[C@@H]2CCNC2)c2nc(N)[nH]c12 |r| Show InChI InChI=1S/C19H20N10O4S2/c1-9-2-3-12(16-15(9)23-19(20)24-16)11-4-5-13(35(32,33)27-10-6-7-22-8-10)17(34(21,30)31)14(11)18-25-28-29-26-18/h2-5,10,22,27H,6-8H2,1H3,(H2,20,23)(H2,21,30,31)/b12-11+/t10-/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0920	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				US Patent US10221163 (2019) BindingDB Entry DOI: 10.7270/Q2RX9FB1
					More data for this Ligand-Target Pair