BDBM361733 US10221177, Compound 96
SMILES: C[C@@H](C(=O)Nc1cncc(n1)-c1cnc(nc1)N1CCC[C@H]1C(F)(F)F)n1cnc2n(C)c(=O)n(Cc3cc(C)on3)c(=O)c12
InChI Key: InChIKey=OKROUULIEINPBH-KXBFYZLASA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human)) | BDBM361733 (US10221177, Compound 96) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Hydra Biosciences, Inc. US Patent | Assay Description Compounds of Formula (I) inhibit the TRPA1 channel, as shown by measuring the in vitro inhibition of human TRPA1, provided in data tables shown in Ta... | US Patent US10221177 (2019) BindingDB Entry DOI: 10.7270/Q2445PR8 | |||||||||||
More data for this Ligand-Target Pair |