BDBM362530 US10562916, Compound 90::US9834564, Compound 90

SMILES: Cn1c(CCc2ccc3ccccc3n2)nc2c1ccc1ccccc21

InChI Key: InChIKey=LNVMMPFSESZEQA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 362530   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM362530 (US10562916, Compound 90 | US9834564, Compound 90) Show SMILES Cn1c(CCc2ccc3ccccc3n2)nc2c1ccc1ccccc21 Show InChI InChI=1S/C23H19N3/c1-26-21-14-11-16-6-2-4-8-19(16)23(21)25-22(26)15-13-18-12-10-17-7-3-5-9-20(17)24-18/h2-12,14H,13,15H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
Sunovion Pharmaceuticals, Inc. US Patent					Assay Description In one embodiment, the compounds provided herein were assayed for their ability to inhibit human PDE-10A. In one embodiment, the activities of the co...				US Patent US10562916 (2020) BindingDB Entry DOI: 10.7270/Q2N87D6K
					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM362530 (US10562916, Compound 90 | US9834564, Compound 90) Show SMILES Cn1c(CCc2ccc3ccccc3n2)nc2c1ccc1ccccc21 Show InChI InChI=1S/C23H19N3/c1-26-21-14-11-16-6-2-4-8-19(16)23(21)25-22(26)15-13-18-12-10-17-7-3-5-9-20(17)24-18/h2-12,14H,13,15H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
Sunovion Pharmaceuticals Inc. US Patent					Assay Description The activities of the compounds were determined using the Molecular Devices IMAP PDE Fluorescence Polarization assay using recombinant human PDE-10 e...				US Patent US9834564 (2017) BindingDB Entry DOI: 10.7270/Q2FF3VN4
					More data for this Ligand-Target Pair