BDBM362560 US10562916, Compound 120::US9834564, Compound 120

SMILES: C(Oc1cnc2ccccc2n1)c1nc(c[nH]1)-c1ccccc1

InChI Key: InChIKey=NXBCETFGYMWKDH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 362560   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM362560 (US10562916, Compound 120 | US9834564, Compound 120) Show SMILES C(Oc1cnc2ccccc2n1)c1nc(c[nH]1)-c1ccccc1 Show InChI InChI=1S/C18H14N4O/c1-2-6-13(7-3-1)16-10-20-17(21-16)12-23-18-11-19-14-8-4-5-9-15(14)22-18/h1-11H,12H2,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
Sunovion Pharmaceuticals, Inc. US Patent					Assay Description In one embodiment, the compounds provided herein were assayed for their ability to inhibit human PDE-10A. In one embodiment, the activities of the co...				US Patent US10562916 (2020) BindingDB Entry DOI: 10.7270/Q2N87D6K
					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM362560 (US10562916, Compound 120 | US9834564, Compound 120) Show SMILES C(Oc1cnc2ccccc2n1)c1nc(c[nH]1)-c1ccccc1 Show InChI InChI=1S/C18H14N4O/c1-2-6-13(7-3-1)16-10-20-17(21-16)12-23-18-11-19-14-8-4-5-9-15(14)22-18/h1-11H,12H2,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
Sunovion Pharmaceuticals Inc. US Patent					Assay Description The activities of the compounds were determined using the Molecular Devices IMAP PDE Fluorescence Polarization assay using recombinant human PDE-10 e...				US Patent US9834564 (2017) BindingDB Entry DOI: 10.7270/Q2FF3VN4
					More data for this Ligand-Target Pair