null

SMILES: Cc1nc(N)nc(N2CCC[C@H]2c2nc3cccc(-c4cccnc4)c3c(=O)n2-c2ccccc2)c1C#N

InChI Key: InChIKey=ZSDLDNPOVCBDFJ-DEOSSOPVSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 362694   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM362694 (US9840498, 20) Show SMILES Cc1nc(N)nc(N2CCC[C@H]2c2nc3cccc(-c4cccnc4)c3c(=O)n2-c2ccccc2)c1C#N |r| Show InChI InChI=1S/C29H24N8O/c1-18-22(16-30)26(35-29(31)33-18)36-15-7-13-24(36)27-34-23-12-5-11-21(19-8-6-14-32-17-19)25(23)28(38)37(27)20-9-3-2-4-10-20/h2-6,8-12,14,17,24H,7,13,15H2,1H3,(H2,31,33,35)/t24-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM362694 (US9840498, 20) Show SMILES Cc1nc(N)nc(N2CCC[C@H]2c2nc3cccc(-c4cccnc4)c3c(=O)n2-c2ccccc2)c1C#N |r| Show InChI InChI=1S/C29H24N8O/c1-18-22(16-30)26(35-29(31)33-18)36-15-7-13-24(36)27-34-23-12-5-11-21(19-8-6-14-32-17-19)25(23)28(38)37(27)20-9-3-2-4-10-20/h2-6,8-12,14,17,24H,7,13,15H2,1H3,(H2,31,33,35)/t24-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM362694 (US9840498, 20) Show SMILES Cc1nc(N)nc(N2CCC[C@H]2c2nc3cccc(-c4cccnc4)c3c(=O)n2-c2ccccc2)c1C#N |r| Show InChI InChI=1S/C29H24N8O/c1-18-22(16-30)26(35-29(31)33-18)36-15-7-13-24(36)27-34-23-12-5-11-21(19-8-6-14-32-17-19)25(23)28(38)37(27)20-9-3-2-4-10-20/h2-6,8-12,14,17,24H,7,13,15H2,1H3,(H2,31,33,35)/t24-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad/CA, USA) (Cat. No. PV5099). The kit contains the fo...				US Patent US9840498 (2017) BindingDB Entry DOI: 10.7270/Q25X2C7X
					More data for this Ligand-Target Pair