null

SMILES: COc1cccc(OC)c1-n1c(NS(=O)(=O)C(C)Cc2ncc(F)cn2)nnc1-c1cccnc1

InChI Key: InChIKey=BGTXYBUAMCBKGR-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 363104   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apelin receptor (Homo sapiens (Human))	BDBM363104 (N-(4-(2,6-dimethoxyphenyl)-5-(3-pyridinyl)-4H-1,2,...) Show SMILES COc1cccc(OC)c1-n1c(NS(=O)(=O)C(C)Cc2ncc(F)cn2)nnc1-c1cccnc1 |(-7.16,-3.61,;-5.82,-4.38,;-4.49,-3.61,;-4.49,-2.07,;-3.16,-1.3,;-1.82,-2.07,;-1.82,-3.61,;-.49,-4.38,;.85,-3.61,;-3.16,-4.38,;-3.16,-5.92,;-1.91,-6.82,;-.58,-6.05,;.76,-6.82,;-.01,-8.16,;1.53,-8.16,;2.09,-6.05,;2.09,-4.51,;3.43,-6.82,;4.76,-6.05,;6.09,-6.82,;7.43,-6.05,;7.43,-4.51,;8.76,-3.74,;6.09,-3.74,;4.76,-4.51,;-2.39,-8.29,;-3.93,-8.29,;-4.4,-6.82,;-5.94,-6.82,;-6.71,-5.49,;-8.25,-5.49,;-9.02,-6.82,;-8.25,-8.16,;-6.71,-8.16,)| Show InChI InChI=1S/C22H22FN7O4S/c1-14(10-19-25-12-16(23)13-26-19)35(31,32)29-22-28-27-21(15-6-5-9-24-11-15)30(22)20-17(33-2)7-4-8-18(20)34-3/h4-9,11-14H,10H2,1-3H3,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	6.40	n/a	n/a	n/a	n/a
AMGEN INC. US Patent					Assay Description The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV-3 expression vector (Sig...				US Patent US9845310 (2017) BindingDB Entry DOI: 10.7270/Q28P62TV
					More data for this Ligand-Target Pair