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SMILES: FC(F)(F)c1ccc(COc2ccc(cc2)-c2nc3cc(cnc3[nH]2)C2CCNCC2)cc1

InChI Key: InChIKey=KFDOBALUKTTZLQ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 364122   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))		BDBM364122
PNG
(US9856252, 14)
Show SMILES FC(F)(F)c1ccc(COc2ccc(cc2)-c2nc3cc(cnc3[nH]2)C2CCNCC2)cc1
Show InChI InChI=1S/C25H23F3N4O/c26-25(27,28)20-5-1-16(2-6-20)15-33-21-7-3-18(4-8-21)23-31-22-13-19(14-30-24(22)32-23)17-9-11-29-12-10-17/h1-8,13-14,17,29H,9-12,15H2,(H,30,31,32)
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/a 1.01E+3n/an/an/an/an/an/a



Bristol-Myers Squibb Company



Assay Description
The 6 μL assay reactions are run in Greiner brand black 384-well low volume plates. All reactions contained assay buffer (phosphate buffered sal...

J Med Chem 49: 2440-55 (2006)


BindingDB Entry DOI: 10.7270/Q2BK1FNV
More data for this
Ligand-Target Pair